CNDR’s 14th Annual Marian S. Ware Research Retreat” “Biomarkers in Neurodegenerative Diseases”

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On Friday, October 3, 2014, Penn’s Center for Neurodegenerative Disease Research (CNDR) hosted their 14th Annual Marian S. Ware Research Retreat which focused on the theme “Biomarkers in Neurodegenerative Diseases.” To discuss this topic, CNDR welcomed a variety of experts in drug development, Alzheimer’s disease, Parkinson’s disease, Frontotemporal Degeneration (FTD) and other neurodegenerative diseases to showcase how biomarkers are currently being used, or can be used, in their field of research. Speakers included Penn affiliates, Jon Toledo, MD, Research Associate, CNDR, Les Shaw, PhD, Director, Biomarker Research Laboratory, Corey McMillan, PhD, Research Assistant Professor, Penn’s FTD Center, David J. Irwin, MD, Instructor in Neurology, Penn’s CNDR and FTD Centers, Rizwan Akhtar, MD, PhD, Clinical Instructor, Department of Neurology, and Alice Chen-Plotkin, MD, Assistant Professor, Department of Neurology, as well as Mark Mintun, MD, President and Chief Medical Officer of Avid Radiopharmaceuticals, Inc., a close partner of CNDR. See agenda for talk titles.

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In addition to the lectures, this daylong event also included a poster session highlighting recent and current projects submitted by Penn affiliates and other various colleagues. Following the last set of lectures, first, second, and third place winners were chosen for the Best Poster Awards.

1st  P L A C E   W I N N E R
100_0145Poster Title: “A directed genetic screen reveals loss of rad-23 as a suppressor of neurodegeneration”
Presented By: Angela Jablonski
Authors: Jablonski AM1, Lamitina T4, Liachko NF5, Liu J6, Mojsilovic-Petrovic J2, Kraemer B5, Wang J6, and Kalb1,2,3
Affiliations: Department of Neuroscience1, Department of Pediatrics, Division of Neurology, CHOP2, Department of Neurology3, Department of Pediatrics and Cell Biology, University of Pittsburg Medical Center4, Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, University of Washington5, Department of Biochemistry and Molecular Biology, John’s Hopkins School of Medicine6

 

2nd  P L A C E   W I N N E R
100_0144Poster Title: “Optineurin is an Autophagy Receptor for Damaged Mitochondria in Parkin-dependent Mitophagy that is disrupted by an ALS-linked mutation.”
Presented By: Yvette Wong
Authors: Yvette C. Wong, Erika L. Holzbaur
Affiliation: Department of Physiology

 

 

 

3rd  P L A C E   W I N N E R
100_0143Poster Title: “Molecular mechanisms of hnRNPA1 and hnRNPA2 misfolding and toxicity”
Presented by: Alice Ford
Authors: Alice Ford1, Lin Guo2, Emily Scarborough2, James Shorter2
Affiliations: Neuroscience Graduate Group, Department of Biochemistry and Biophysics1, Department of Biochemistry and Biophysics2

 

 

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