Activating and Remodeling Dysfunctional Brain Circuits using Deep Brain Stimulation in Alzheimer’s Disease

Last week, the Institute on Aging wrapped up their 2015 Visiting Scholars Series with Andres Lozano, MD, PhD, Chair, Division of Neurosurgery at University of Toronto. Dr. Lozano is a neurosurgeon interested in developing novel therapies to treat neurologic and psychiatric disorders. He is particularly interested in functional neurosurgery, which is aimed at improving the function of the brain.

One technique commonly used is Deep Brain Stimulation, a procedure that involves placing electrodes in brain to chronically deliver electricity to any malfunctioning brain circuits 24 hours a day. This technique is currently being used to treat an estimated 125,000 Parkinson’s disease patients throughout the world and is now being explored as a treatment for Alzheimer’s disease.

Rather than connecting the electrodes to the circuits that control movement, as they do in Parkinson’s patients, Dr. Lozano and his team are looking into targeting the circuits that control memory and cognition to assess the safety and potential benefit for Alzheimer’s patients.

Learn more about Dr. Lozano and his research using deep brain stimulation here:

 

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