On Thursday, October 27, 2016, the Institute on Aging hosted its 2016 Joseph A. Pignolo Award in Aging Research event. The recipient of this year’s award — which is given annually to recognize significant contributions in the field of aging research — was Luigi Ferrucci, MD, PhD, an epidemiologist and geriatrician who is currently the Scientific Director of the National Institute on Aging (NIA) and Chief of the Longitudinal Studies Section.
During his lecture on “The Mechanisms of Age-related Loss of Muscle Biomechanical Quality,” Dr. Ferrucci discussed his work on trying to uncover the reasons why we lose muscle mass and strength in aging. “The important thing to understand is not why the muscles shrink, but why we lose muscle quality,” he said.
Watch the video below for a summary of Dr. Ferrucci’s lecture:
Dr. Ferrucci also shared a glimpse into other research happening at the NIA, including a relatively new study in which they selected a small population of healthy individuals in hopes of understanding their secret to maintaining their health in old age. They are conducting in-depth analyses of genomes, epigenetics, blood, and other tissue samples including muscle and skin biopsies. Through their research, they hope to develop technologies that do not require such labor-intensive interventions to be measured and can apply them to new generations of epidemiological studies of aging.
Dr. Ferrucci received the 2016 Pignolo Award in Aging Research for his 2015 publication, “Gene expression markers of age-related inflammation in two human cohorts,” in Experimental Gerontology. His research focuses primarily on the causal pathways leading to progressive physical and cognitive decline in older persons, and in particular, inflammation.
This publication was an attempt for Dr. Ferrucci and his colleagues to look at the genetics of aging in a “somewhat nontraditional way,” he said.
To read the full publication, click here.